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Outsmarting the Number One Killer
A Science-based Program for Reversing
Atherosclerotic Plaque, Heart Attacks
and Strokes
by
Timothy J. Smith, M.D.
Original Book from Internet
Contents
0 Preliminary
I The Disease
1 A Journey of the Heart
2 Atherosclerosis: The Silent Killer
3 Hal, Celeste, Art, Jake and Chip: Five Case Studies
4 An Epidemic of Staggering Proportions
5 Atherogenesis: How Arteries Fail
6 How to Get Tested and Design Your Heart Program
II The Markers
7 The Lipid Panel: Cholesterol, LDL, Triglycerides, HDL, VLDL
8 C-Reactive Protein: The fire alarm molecule
9 Homocysteine: Sandblaster From Hell
10 Fibrinogen: Clotting Factor and Inflammatory Protein
11 Blood Sugar, Insulin Resistance, and The Metabolic Syndrome
12 LDL Particle Size: A Few Nanometers Can Spell the Difference Between Life and Death
13 Appendix
Detailed Contents
0 Preliminary
0.1 Original table of contents
0.2 Front page
I The Disease
1 A Journey of the Heart
1.1 Dad's heart attack
1.2 Shadowing Dr. Swank
1.3 Zebras and chickens
1.4 Bypass surgery
1.5 Mr. Fan has a heart attack
1.5.1 Dancing with death
1.5.2 Some causes of endothelial dysfunction
1.5.3 Solving the riddle of atherosclerosis
2 Atherosclerosis: The Silent Killer
2.1 Our current (dysfunctional) approach to vascular disease
2.2 A shift of consciousness is required
2.3 Rethinking atherosclerosis, the "number one killer"
3 Hal, Celeste, Art, Jake and Chip: Five Case Studies
3.1 Hal
3.2 Celeste
3.3 Art
3.4 Jake
3.5 Chip
4 An Epidemic of Staggering Proportions
4.1 This is an epidemic
4.2 Our outmoded system
4.3 A new approach
4.4 The six heart markers
4.5 Additional markers
4.6 Risk markers versus risk factors
4.6.1 Risk factors for atherosclerosis
5 Atherogenesis: How Arteries Fail
5.1 Atherosclerosis starts early and develops gradually
5.2 Anatomy of an artery
5.3 Phase one: endothelial injury
5.3.1 Causes of endothelial dysfunction
5.4 Preventing endothelial damage
5.5 Phase two: plaque formation
5.6 Phase three: thrombus formation, rupture, and disaster
6 How to Get Tested and Design Your Heart Program
6.1 The cardiovascular risk marker panel
6.2 How and where to get tested
6.3 Insurance coverage and low-cost testing
6.4 When your results come back
6.5 About normal ranges
6.6 Interpret your test results and design your program
6.7 Follow-up testing is crucial to your success
6.7.1 After 8-12 weeks, retest
6.8 Additional risk markers for cardiovascular disease
6.9 A note about supplements
II The Markers
7 The Lipid Panel: Cholesterol, LDL, Triglycerides, HDL, VLDL
7.1 Lipoproteins
7.1.1 Components of a lipid panel
7.2 Cholesterol: good or evil?
7.2.1 Cholesterol's image problem
7.2.2 Where does cholesterol come from?
7.2.3 Cholesterol transport into the cell
7.2.4 Cholesterol: a weak marker for atherosclerotic disease
7.3 LDL: little balls of fat
7.3.1 Why LDL is important - the cholesterol - atherosclerosis connection
7.3.2 Oxidized LDL - the real culprit
7.3.3 Size matters too
7.3.4 Unstable plaque: exceptionally dangerous
7.3.5 What's an ideal cholesterol and LDL level?
7.3.6 Lowering cholesterol works
7.3.7 Keeping cholesterol and LDL in perspective
7.4 How to lower your cholesterol and LDL
7.4.1 Basic program to lower cholesterol and LDL
7.4.2 Red yeast rice extract
7.4.3 Pomegranate juice
7.4.4 Curcumin
7.4.5 Green tea extract (Camilla sinensis)
7.4.6 Garlic
7.4.7 Flaxseed oil
7.4.8 Marine lipids (fish oil; EPA and DHA)
7.4.9 Dietary changes that will lower your cholesterol and LDL
7.4.10 Lifestyle cholesterol and LDL lowering agents
7.4.11 Make sure you are not hypothyroid
7.4.12 Additional cholesterol and LDL-lowering agents
7.4.13 Drugs* that lower cholesterol and LDL
7.5 Triglycerides your fat transport system
7.5.1 What is a triglyceride?
7.5.2 The importance of triglycerides
7.6 How to lower your triglyceride level
7.6.1 Basic program for lowering triglyceride level
7.6.2 Additional nutritional medicines that lower triglycerides
7.6.3 These dietary changes will lower your triglycerides
7.6.4 Lifestyle changes that lower triglycerides
7.6.5 Correct subclinical hypothyroidism
7.6.6 Factors that cause triglycerides to go up
7.6.7 Drugs* that lower triglycerides
7.7 HDL
7.7.1 What are HDL particles and what do they do?
7.7.2 Why is a high HDL level so important?
7.7.3 HDL protects against atherosclerosis by depriving macrophages of their lunch
7.7.4 Some recent research revelations about HDL
7.8 How to boost your HDL level
7.8.1 Recommended program for raising HDL
7.8.2 Diet to raise HDL
7.8.3 Lifestyle changes that raise HDL
7.8.4 Additional supplements that increase HDL
7.8.5 Drugs* that raise HDL
7.9 VLDL
7.10 How to lower your VLDL level
8 C-Reactive Protein: The fire alarm molecule
8.1 What is CRP?
8.2 Common causes of inflammation
8.3 Smoking gun or innocent bystander?
8.4 What is a normal CRP?
8.5 How to Lower Your Elevated C-Reactive Protein
8.5.1 Recommended program to lower your C-Reactive Protein
8.5.2 Diet to lower CRP
8.5.3 Lifestyle factors that lower CRP
8.5.4 Additional methods to lower C-Reactive Protein
8.5.5 Drugs that lower CRP*
9 Homocysteine: Sandblaster From Hell
9.1 Chuck has a busy week
9.2 What is homocysteine?
9.3 Many diseases are associated with excess homocysteine
9.4 Widespread damage
9.5 Where does homocysteine come from?
9.6 Misunderstood by mainstream doctors
9.7 Checking homocysteine saves lives
9.8 Lowering Chuck's elevated homocysteine
9.9 What is optimum?
9.10 Homocysteine: poster child for a flawed approach to cardiovascular disease
9.11 How to lower your elevated homocysteine
9.11.1 Recommended program to lower your homocysteine
9.11.2 Additional nutrients that lower homocysteine
9.11.3 Avoid these factors that cause homocysteine elevation
10 Fibrinogen: Clotting Factor and Inflammatory Protein
10.1 Elevated fibrinogen both predicts and causes cardiovascular disease
10.2 Not an innocent bystander
10.3 Brent Chadwick: an attorney with an elevated fibrinogen level
10.4 Fibrinogen plays major roles in inflammation management and clot formation
10.5 Excess fibrinogen causes clots and thrombi
10.6 Fibrinogen manages inflammation, warns of inflammation ... and causes it!
10.7 If fibrinogen elevated, test more than once
10.8 High fibrinogen especially dangerous when any other heart marker is elevated
10.9 Lowering your elevated fibrinogen
10.9.1 Nattokinase
10.9.2 Curcumin (a component of the herb turmeric)
10.9.3 Serrapeptase
10.9.4 Flaxseed oil
10.9.5 Bromelain
10.9.6 Green tea
10.9.7 Diet to lower fibrinogen
10.9.8 Fibrinogen-lowering lifestyle
10.9.9 Additional fibrinogen-lowering nutritional medicines
10.9.10 Drugs that lower fibrinogen
11 Blood Sugar, Insulin Resistance, and The Metabolic Syndrome
11.1 "Please calm down, Mr. Shoemaker."
11.2 The Metabolic Syndrome (TMS)
11.3 Insulin resistance
11.4 As we get older TMS will affect most of us
11.5 Why should I care if my blood sugar is elevated?
11.6 How can I tell whether I have TMS? The five cardinal signs of The Metabolic Syndrome
11.7 The "disease of the new millennium"
11.8 Insulin resistance: the driving force behind TMS
11.9 Most people can reverse TMS by lowering carb consumption and exercising every day
11.10 How to Reverse Insulin Resistance and The Metabolic Syndrome
11.10.1 Recommended program overview
11.10.2 Low carb dieting
11.10.3 Exercise
11.10.4 Cinnulin cinnamon extract
11.10.5 Alpha lipoic acid
11.10.6 Glucose Control
11.10.7 Chromium, flaxseed oil
11.10.8 Address other markers for TMS
11.10.9 Lower your blood pressure
11.10.10 Weight loss (getting rid of the abdominal fat)
12 LDL Particle Size: A Few Nanometers Can Spell the Difference Between Life and Death
12.1 Bigger is better and small is not beautiful
12.2 Can a billionth of a meter change your life?
12.3 Pattern "A" is "All right" but pattern "B" is "Bad"
12.4 Type "B" more easily oxidized
12.5 Don't confuse LDL particle size with LDL number
12.6 Testing for LDL particle size
12.7 The triglyceride/HDL shortcut
12.8 How to increase your LDL particle size (from bad pattern "B" to all right pattern "A")
12.8.1 Low carbohydrate diet, daily exercise, weight loss.
12.8.2 Lower your triglycerides
12.8.3 Raise your HDL levels (if low, which they probably are)
12.8.4 Lower your blood sugar levels (if elevated)
12.8.5 Nutritional medicines that increase LDL particle size
12.8.6 Drugs* that increase LDL particle size
13 Appendix
13.1 Final thoughts
13.2 About the author
13.3 More information
13.4 References